Synthesis of (-)-ilimaquinone via a radical decarboxylation and quinone addition reaction.
نویسندگان
چکیده
[reaction: see text] A stereoselective synthesis of (-)-ilimaquinone (4) is presented. The synthetic strategy is based on a novel radical decarboxylation and quinone addition methodology that produces quinone 7 from reaction of thiohydroxamic acid derivative 8 with benzoquinone (9). Final functionalization of 7 to ilimaquinone (4) is achieved by exploring the electronic effects of the residual thiopyridyl group.
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عنوان ژورنال:
- Organic letters
دوره 4 5 شماره
صفحات -
تاریخ انتشار 2002